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Geftinat Tablets are anticancer medicine that works by inhibiting epidermal growth factor receptors. They are formulated using geftinib as active compound with chemical formula C22H24ClFN4IO3 and molar mass of 446.902 g/mol. These tablets are known to have excellent protein binding ability of 90% with bioavailability of 59%. Geftinat Tablets binds to adenosine triphosphate binding site of tyrosine kinase, thus resulting in inhibition of EGFR.
Have elimination half life of 6 to 49 hours depending upon concentration
Gets metabolized in liver by CYP3A4 enzyme
Excreted in feces