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Afinitor Tablets have been formulated using everolimus as main compound that is known to play an important role in organ transplants. They are considered as mTOR inhibitors and this activity serves as targeted therapy for various cancers. These tablets have 5mg of active ingredient and are prescribed according to patient condition. Afinitor Tablets work by binding to FKBP12 protein receptors resulting in inhibition of mTORC1 downstream signaling. They are not known to inhibit mTORC2 complex which plays an important role in immune system and glucose metabolism.
Assist in cell survival and growth
They are a type of immunosuppressant
Have ability to activate kinase AKT