Axitinib Tablet is prescribed to be consumed in treatment of renal cell carcinoma and various types of tumors. It has been formulated using axitinib as active compound having chemical formula C22H18N4OS and molecular mass of 386.469 g/mol. This tablet works by inhibition of angiogenesis by inhibiting PDGFR, c-KIT, and vascular endothelial growth factor receptor 1-3. Axitinib Tablet is known to have bioavailability of around 58% and gets metabolized by CYP3A4 & CYP3A5 enzymes in liver.
Has excellent protein binding ability of more than 99%
Excreted in feces and urine
Has elimination half life of 2.5 to 6.1 hours